We propose a review of the literature of the studies investigating reading acquisition in intellectual deficiency (ID), with particular focus on the explanatory factors for reading difficulties. Indeed, we explore the role of intellectual efficiency, perceptual abilities, oral language development, phonological processing and memory. The study of reading acquisition in ID is a challenge because of a high degree of heterogeneity in the results which, together with other variables influencing learning and development. This review has allowed us to understand that there are multiple reasons why individuals with ID have difficulty learning to read. More specifically, there is a link between reading skills and certain cognitive skills, such as perception, oral language, phonological processing and working memory.