In this article, we examined predictive validity of "Student Risk Screening Scale for Internalizing and Externalizing" (SRSS-IE) scores for use at the middle (N = 2,313 from four middle schools) and high (N = 2,727 from two high schools) school level. Results indicated middle and high school students with high levels of risk according to fall SRSS-IE scores (particularly those with externalizing behaviors) were likely to have lower grade point averages, fail more courses, have more nurse visits, and spend more time in in-school suspensions compared with students at low risk for externalizing and internalizing behaviors. Education implications, limitations, and future directions are presented.