Advancements in item response theory (IRT) have led to models for dual dependence, which control for cluster and method effects during a psychometric analysis. Currently, however, this class of models does not include one that controls for when the method effects stem from two method sources in which one source functions differently across the aspects of another source (i.e., a nested method-source interaction). For this study, then, a Bayesian IRT model is proposed, one that accounts for such interaction among method sources while controlling for the clustering of individuals within the sample. The proposed model accomplishes these tasks by specifying a multilevel trifactor structure for the latent trait space. Details of simulations are also reported. These simulations demonstrate that this model can identify when item response data represent a multilevel trifactor structure, and it does so in data from samples as small as 250 cases nested within 50 clusters. Additionally, the simulations show that misleading estimates for the item discriminations could arise when the trifactor structure reflected in the data is not correctly accounted for. The utility of the model is also illustrated through the analysis of empirical data.