Both process- and product-oriented, this study presents estimates the effects of using computer and multimedia software on students' learning and their perceptions of chemistry classroom environment. 44 Iranian first-grade high school students were divided into control and treatment group. They were taught parts of the second grade high school chemistry textbook during 15 sessions. The control group was taught using just the textbook and the ordinary equipment while the treatment group was taught using computer, educational software, PowerPoint files and LCD monitor beside the textbook and the ordinary equipment. After 12 sessions, the WIHIC (What Is Happening In This Classroom) questionnaire was administered among the participants and at the end, a final test was also given to both groups to assess the participants' learning. The results revealed that the participants in the treatment group perceived their chemistry classroom environment more positively and gained better scores.