UNESCO's new emphasis on vocational education and training as transformative, and concerns in particular with equity and sustainable human development, has been strongly influenced by a recent literature on VET and human development that has a particular focus on the most marginalised, especially young women, and is concerned with how their aspirations, agency and achievement of wellbeing can be promoted in the face of wide-ranging structural obstacles. This article seeks to further develop that account through an even stronger emphasis on VET in the context of extreme poverty, inequality and marginalisation as faced in Palestine. VET in Palestine serves many of the poorest and most disenfranchised in Palestinian society in a context of profound structural obstacles to wellbeing achievement. Our analysis show a very positive story of how VET has helped highly disadvantaged young Palestinians, particularly young women, to make progress on their human development.