The study investigated the challenges faced by the prospective teachers during teaching practice. The sample of the study comprised 34 prospective teachers enrolled in the final semester of B.Ed. (Hons.) program at University of the Punjab and University of Gujrat. The prospective teachers were trained in using student-centered pedagogies in teaching practice. Data analysis revealed that there was a noticeable transformation towards the use of teaching methods other than lecture method in their classroom. The major challenges included dealing with poor physical infrastructure, scarce and underused academic resources, inflexibility in classroom arrangement, non-professional attitude of school administration, and trying out innovation without challenging the prevailing school norms. Teaching practice has helped prospective teachers to strike a balance between their expectations and reality of schools and classrooms. A closer interaction among university, school, prospective teachers and students beyond teaching practice is essential to increase mutual familiarity addressing the surprise element of challenges faced by the prospective teachers.