The NGSS MS-ETS1 Engineering Design (1-4) is the focus of the article. Development of a challenging problem-based activity that is an improvement over the traditional egg drop competition is emphasized. Quantification of data collected and real-world relevance are two activity components that are viewed as improvements over the egg drop. The article describes a set of lessons that prepares pharmaceutical companies to drop medicine into the Amazon Rain Forest. Lessons 1-2 involve planning and parachute variable testing (e.g., weight, string length, number of strings, parachute size/shape, etc.) to measure changes in descent rates. Lesson 3 involves building a prototype using small dosage cups, parachute making materials and other random materials (e.g., larger cups, popsicle sticks, etc.). And, Lesson 4 has groups build a final parachute to drop an open container of liquid medication into a remote village. The challenge involves having to use an open container for the medication to remain effective. Due to expense, medication spillage is not permitted. Amount that spills provides a data point to assess performance.