The main goal of this study is to investigate the extent to which a computer-based flashcard program, Anki, can help college-level ESL learners improve their vocabulary as well as the learners' perceptions about the program. The vocabulary targeted for the study consisted of Coxhead's (2000) "Academic Word List", including the most common words in university textbooks. An academic vocabulary dictionary which encompasses 210 academic words was designed for the study and thirteen students coming from two ESL classes used the Anki dictionary for ten minutes every day during the three week intervention process. Pretest and posttest scores of students were compared to evaluate the effectiveness of the learning process. Learners` perceptions about the training were investigated by means of surveys, interviews and observations. The results present the benefits that might be gained from the integration of flashcard programs into a language classroom, as well as the perceptions of learners about the process.