Vocabulary as an undeniable part of language learning is a main component in communication which requires to be taught in innovative ways. The purpose of this study was to examine the effect of musical mnemonic on vocabulary recalling, and long-term retention of words by young learners. The design of study was experimental. Sixty teenagers from Shokoh Language Institute in small town of Khorramdare, Iran participated in the study. To conduct the study, participants were divided into experimental and control groups. A list of 14 words were harmonized to melody of mentioned song and recorded in a professional studio. Validity of the words were examined by Lawsh CVR (Content Validity Ratio) and CVI (Content Validity Index). The results from Independent T-Tests indicated that experimental group outscored control group. Regarding research questions, it was found that musical mnemonic improves vocabulary recalling of experimental group in comparison to control group. In addition, results related to research questions showed that musical mnemonic help learners better understand words in new contexts. The findings imply that musical mnemonic can improve memory, and comprehension by practicing, and using melodic and rhythmic information.