The purpose of current research is to study the effect of knowledge sharing on the psychological empowerment of faculty members considering the intermediary (mediating) role of organizational memory in Semnan University. To study research variables, three standard questionnaires were distributed among 334 faculty members of the studied sample. Structural equation modeling has been used to test the hypotheses. Results show a meaningful effect between knowledge sharing and empowerment. They also show that organizational memory plays an intermediary role in affecting knowledge sharing over empowerment of faculty members. The important message for Semnan University is creation of strong cultural academic in accepting organizational memory and participating in the process of its creation and its implantation in forms of systems that facilitates the process of sharing knowledge by faculty members. Also, the empirical findings of this study will develop the literature on knowledge sharing, empowerment and organizational memory in higher education institutions.