The study set out to investigate what influences the intentions of college students to get vaccinated against genital human papillomavirus (HPV). College men and women were surveyed to understand their intentions. Regression was used and supported that the constructs of the health belief model (HBM) as well as gender, norms, and information seeking contributed to predicting intent to receive the HPV vaccine, R2 = 0.61, F(6, 159) = 39.41, p < 0.001. Benefits and barriers were the most influential variable, and men were more likely to intend to receive the vaccine. The findings should be applied to future campaigns aimed at increasing preventive health behaviors, especially vaccinations among college students.