The main aim of the study was to assess the accessibility, adequacy and use of ICT in Distance Education (DE) programme of the University of Ghana (UG), Legon distance learning students. Information Communication Technology (ICT) plays a critical role in enhancing the teaching and learning processes of the DE programme. Both interview and questionnaires were used as instruments for collecting data from the management staff and distance learning students respectively. The main findings of the study were that the inaccessibility and inadequacy of ICT facilities had affected students' academic work especially in the area of research, learning and even library services. Moreover, the findings confirmed that a strong relationship exist between 'adequacy of ICT facilities' and teaching, learning and research'. A regression test found out that there is a positive, very strong and significant relationship (r= 0. 814, p < 0.01) between adequacy of the facilities/resources and academic performance.