The purpose of this research is to examine which factors of personal meaning profile explain mental well-being in different age stage. Although personal meaning has many different definitions, this research approaches it in seven factors; achievement, relationship, religion, self-transcendence, self-acceptance, intimacy, and fair treatment. The participants in this study were 410 (226 female, 184 male) representing three separate groups (Adolescents, emerging adults, and adults). Whether Personal meaning and mental well-being varied based on age was analyzed via ANOVA. Personal Meaning's predictability of mental well-being was analyzed via multiple regression analysis. First, the mental well-being productivity of personal meaning in the whole group was examined. According to the examination, it was found that all factors except for religion explain mental wellbeing. These factors account for 54% of the variance. Secondly, multiple regression analysis was done for the personal meaning factors for each group. According to results: Achievement, relationship, and self-transcendence in adolescents; achievement, self-transcendence, self-acceptance, intimacy, and fair treatment in emerging adults; and intimacy, self-transcendence, self-acceptance and fair treatment in adults were significant predictors mental well-being. These factors account for 43% of total variance in adolescent, 65% in emerging adults, and 42% in adults.