Problem Statement: Annual gynecological exams could be a strategy to increase initiation and completion of HPV vaccination series among female college students. However, few studies have examined the role these exams play in vaccination uptake. This study assesses the association of OB/GYN visitation and HPV vaccine uptake among female college students on a metropolitan campus in the Southeastern United States. Methods: Participants were 356 female students aged 18 to 30, who completed the National College Health Assessment -- II (NCHA-II) during the spring semester of 2010. Descriptive statistics and ?[superscript 2] tests were used to assess OB-GYN visitation and HPV vaccination rates. Logistic regression assessed the magnitude of the association between annual gynecological exam and HPV vaccine uptake. Findings: Among this sample, approximately 63% reported OB/GYN visitations. An HPV vaccination was received by 43% of female college students. Women who visited the OB/GYN during the past 12 months reported 1.82 greater odds of receiving the vaccine compared to non-visitors. Conclusions: OB/GYN visitation may be linked with HPV vaccine uptake among female college students. HPV health prevention programming during OB/GYN visits may be beneficial among college female students. More research is needed to improve access to the HPV vaccine among college students.