In this paper, we explain the influence of co-worker trust on the effect of employees' openness to experience on their perceptions of their own creativity. We surveyed 199 working professionals in Ireland and found that openness to experience was positively associated with both employees' perceptions of their radical creativity and incremental creativity. In addition, the relationship between openness to experience and incremental creativity was negatively moderated by cognition-based trust in his or her co-worker. In conclusion, we discuss the theoretical and managerial implications of our findings and highlight directions for future research.