The aim of this paper is to measure the anxiety toward mathematics of undergraduate medical students in a public university. In order to get the data were surveyed 208 students enrolled when the test was applied. The questionnaire used was the scale of Mato and Muñoz-Vázquez (2007). The statistical procedure was exploratory factorial analysis (EFA) with extraction method: Principal Component Analysis (PCA), Rotation Method: Varimax with Kaiser Normalization (KMO, Bartlett test of Sphericity, MSA, X[superscript 2] with df, a = <0.05). The result suggests that the factor ANXTMSDL (0.933) is the largest factor load, which suggests that the profile of the medical student, generates greater anxiety when faced with operations in daily life and the factor (ANXTT 0.626) is the factor that has a lower factor load, which leads us to think that anxiety towards the temporality of assessments or exams is not present, perhaps because, in the curriculum of the majoring the topics of mathematics are not integrated.