It has been said that the debate over effectiveness of learning online has ended and that several large-scale studies are reporting better learning outcomes for online learning than for some face-to-face courses. In the Central Region of Ghana, a study was carried out to explore opportunities, challenges and expectations confronting adults who learn online. Adult learners' completed a survey modeled on a five-point Likert scale. One hundred and fifty respondents from two districts completed the survey. Respondents perceived their greatest opportunity to be earning a degree online while maintaining their job. Their greatest challenge was with interactivity. Respondents expected information in online courses to be communicated clearly and also be provided with feedback on their progress.