An established methodology involving the sequential presentation of five skills on ASPEN Plus to undergraduate seniors majoring in ChE is presented in this document: (1) specifying unit operations; (2) manipulating physical properties; (3) accessing variables; (4) specifying nonstandard components; and (5) applying advanced features. This manuscript does not attempt to teach the software, nor does it contain teaching materials for use by instructors. Lecture resources drawn from numerous sources are available online on the homepage of the author on the Chemical Engineering Department's web server at New Mexico State University (www.chemeng.nmsu.edu). Demonstration files can be obtained from the author, as well as the Knowledge Base of the ASPENTech website (www.aspentech.com).