Students with persistent and severe reading difficulties pose a significant challenge for educators. The primary purpose of this article is to provide a detailed demonstration of data-based individualization (DBI) implementation in the area of reading. Also provided are various resources a teacher may access to learn more about the instructional strategies included in this article's hypothetical example. The authors describe an example of a special education teacher and one of her students, implementing DBI throughout his fourth grade year. Most students who need DBI will have demonstrated insufficient response to previous remediation attempts. Therefore, the teacher when preparing to implement DBI, should follow a checklist for getting started which includes: (1) selecting an instructional platform; (2) determining how to intensify the platform; (3) making a progress-monitoring plan; (4) setting instructional goals; and (5) making final preparations. The authors intended for this hypothetical example to highlight the feasibility of implementing DBI, which, although it may require additional work, is well worth the potential improvements in student outcomes.