This study used an ecological, person-centered approach to identify subgroups of families who had similar profiles across multiple dimensions of Mexican-origin mothers' and fathers' occupational characteristics (i.e., self-direction, hazardous conditions, physical activity) and to relate these subgroups to families' sociocultural characteristics and youth adjustment. The study included 160 dual-earner Mexican-origin families from the urban Southwest. Mothers' and fathers' objective work characteristics and families' sociocultural characteristics were assessed when youth were in early to middle adolescence; adjustment was assessed during late adolescence and early adulthood for 2 offspring in each family. A latent profile analysis identified 3 profiles that evidenced distinct patterns of occupational characteristics: a "differentiated high physical activity" profile characterized by high levels of physical activity and low levels of self-direction; an "incongruent" profile characterized by large differences between parents on self-direction, hazards, and physical activity; and a "congruent highly self-directed" profile characterized by congruence across parents on occupational characteristics. These profiles were linked to sociocultural characteristics (i.e., family income, educational attainment, and acculturation) and to relational adjustment (i.e., mother- and father-youth conflict, father warmth) and educational aspirations. Results are discussed with respect to implications of parents' work for youths' future family relationships and attainment.