Adolescents present a unique collection of characteristics and challenges which middle school interdisciplinary teams were designed to address. This article describes a research study which explored parental involvement strategies employed by interdisciplinary teaching teams from three very different middle schools: an affluent suburban school, a mid-level rural school, and a high-poverty urban school. A multiple-case study approach was used, and interdisciplinary teams at each middle school were interviewed, responded to journal questions, and were observed at parent nights and related events. Parents were also included as participants through focus groups, one-on-one interviews, and written questionnaires. The researcher identified themes within each setting, as well as four cross-case themes. All of the interdisciplinary teams in this research study utilized strategies grounded in a belief regarding the essential role parental involvement plays, maintained an open and approachable attitude toward parents, served as a resource to parents, and approached problem-solving opportunities as a team. The findings of this study serve as a bridge between what is known about adolescent development, best middle school interdisciplinary teaming models, and the essential nature of parental involvement in education.