This study presents the findings of an internal systems change evaluation of the U.S. Agency for International Development (USAID) Opportunity 2.0 activity in the Philippines, implemented by the Education Development Center (EDC). Known as "O2," the activity aimed to improve second-chance opportunities for 180,000 Filipino out-of-school youth (OSY) in 15 cities throughout the country, thereby improving their future education, employment, and livelihood outcomes. Designed to promote sustained and scalable shifts at the system level, O2 engaged several national and local government agencies, the private sector, OSY and the organizations representing them, education and training service providers, youth-serving organizations, and families and community groups. O2's holistic design was intended to empower OSY to socially and economically engage in their communities. Conducted toward the end of the five-year activity, this evaluation sought to answer this primary question: Over the life of the program, what have been the most salient system-level changes observed by stakeholders in the Philippines education-to-employment system for out-of-school youth?