This quantitative correlational study was conducted to determine if and to what extent Stress mediated the relationship between Harmonious Passion, Obsessive Passion, and Burnout among college students at a university in the South-Central United States. Harmonious Passion and Obsessive Passion were the predictor variables; Stress was the mediator variable; three Burnout's dimensions, Exhaustion, Cynicism, and Efficacy served as criterion variables. Six research questions guided this study: the first group of research questions focused on the extent to which Stress mediated the relationship between Harmonious Passion and each criterion variable; the second group of research questions focused on the extent to which Stress mediated the relationship between Obsessive Passion and each criterion variable. 199 participants provided complete data on the variables of interest. The theoretical foundations for this study were the Multidimensional Theory of Burnout, the Conservation of Resources Theory, and the Dualistic Model of Passion. Using simple and multiple linear regression analyses, the results of this study showed there was a statistically significant full mediated effect of Stress between Harmonious Passion and Exhaustion, F(2, 196) = 50.050, p < 0.0001. adj R[superscript 2] = 0.331; a statistically significant partial mediated effect of Stress between Harmonious Passion and Cynicism, F(2, 196) = 35.402, p < 0.0001. adj R[superscript 2] = 0.258; and a statistically significant partial mediated effect of Stress between Harmonious Passion and Efficacy, F(2, 196) = 43.101, p < 0.0001. adj R[superscript 2] = 0.298. However, Stress did not mediate the relationships between Obsessive Passion and any of the criterion variables. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com.bibliotheek.ehb.be/en-US/products/dissertations/individuals.shtml.]