Thriving at work is a psychological construct associated with being well and doing well in the workplace and is operationalized as a composite score of vitality and learning. The problem addressed by this study was the growing concern that a composite score for thriving at work does not account for how the sub-components of vitality and learning may be differentially associated with important outcomes. The purpose of this quantitative correlational research study was to determine how various combinations of the two components of thriving at work related to job satisfaction and burnout in teachers during the COVID-19 pandemic. Survey data from a sample of 148 K-12 teachers in the US, recruited by Qualtrics, were analyzed using polynomial regression with response surface analysis. Results showed high levels of both vitality and learning (i.e., high thriving) were associated with more favorable outcomes than low levels of the sub-components (i.e., low thriving), as the socially embedded model of thriving at work would predict. The results also provided new insight into how other combinations of vitality and learning relate to satisfaction and burnout. Combinations of vitality and learning that produced mid-level thriving scores revealed a wide range of less desirable outcomes, particularly at the extremes of low vitality/high learning. This finding suggests possible tipping points where increased learning without accompanying vitality leads to increased emotional exhaustion and depersonalization. Based on these results, it is recommended that researchers, administrators and policymakers, and individual teachers recognize the potential of thriving at work to influence important outcomes and begin to take actions to assess, monitor, and influence teachers' levels of vitality and learning. Further research is recommended after the pandemic to determine if and how the results differ. Researchers might also extend the current results to determine if combinations of vitality and learning in teachers are related to student outcomes. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com.bibliotheek.ehb.be/en-US/products/dissertations/individuals.shtml.]