Private higher education institutions in Ghana involved in continuing and professional education have multiple affiliations with diverse public and foreign universities as a result of the varied programs offered. Using the three main isomorphic classifications of DiMaggio and Powell's (1983) institutional theory namely coercive, mimetic and normative, this paper explored the strategies, modalities and challenges bearing on participants in 10 purposively selected mentee private higher education institutions involved in continuing and professional education as well as two quality assurance officials. This paper further examined stakeholder participation in the affiliation process. Data collection procedures consisted of a semi-structured open-ended interview protocol for twelve participants. In addition, institutional documents from the websites of mentee institutions were analyzed. The outcome indicates the state of affiliation processes in private institutions providing continuing and professional education in Ghana. Participants noted among others that affiliating institutional selection is indicative of the types of programs offered by the mentee institution. Some of the challenges enumerated included the timeconsuming nature of the affiliation process and conflict over mentee/mentor expectations. Mentee institutions advocate that there should be a standardization of affiliation fees paid by private higher education institutions offering continuing and professional education. [For the full proceedings, see ED665621.]