Artificial intelligence has potentiated changes in higher education. In this position paper, we propose to discuss dimensions that shape higher education and that can be transformed by the mobilization of Artificial Intelligence: teaching-learning processes (from the perspectives of scholars and students), research (from the perspective of professional researchers, students and advisors), management of organizations (from the perspective of managers, subordinates and students), and the relationship with the outside (the look from inside to outside, as well as from outside to inside). To this end, a document collection and analysis was carried out to support our argument about the new challenges and the potential that emerges from the existence and application of artificial intelligence in higher education. As this change, like any transformation, will have positive and negative aspects, some implications of both a theoretical and more practical nature of these challenges for academics, students and other stakeholders in higher education institutions are also discussed. [For the full proceedings, see ED654100.]