In December 2018, the National Science and Technology Council's (NSTC) Committee on STEM Education (CoSTEM) released "Charting a Course for Success: America's Strategy for STEM Education" (ED590474), a five-year strategic plan for STEM education. The intent of this progress report is to provide Congress and the wider science, technology, engineering, and mathematics (STEM) education stakeholder community an update on the Federal activities that occurred from June 2020 to February 2021. This progress report includes: a summary of Federal Coordination in STEM Education (FC-STEM) progress on the implementation of the STEM strategy, a description of the ways Federal agencies will work together to address common challenges, and an inventory of Federal STEM education programs. The annual report includes actual investments for FY2020, estimated investments for FY2021, and requested funding levels for FY2022. [For the 2020 report, see ED625836.]