Social and emotional learning (SEL) is critical for preparing students for college and career success. Integrating SEL into academic instruction in meaningful ways supports students' SEL development. The Aspen Institute National Commission on Social, Emotional, and Academic Development (2019) identified three important elements for supporting students' SEL: (1) setting a positive climate by establishing safe, relationship-based, and equitable learning environments; (2) teaching and practicing social, emotional, and cognitive skills (i.e., offering explicit SEL instruction); and (3) embedding social, emotional, and cognitive skills into academic instruction (i.e., integrating SEL into academic instruction) (Schwartz et al., 2020). During a four-year, in-depth research study of Opportunity by Design (ObD) high schools (Steiner et al., 2020), the authors observed substantial variation in how schools implemented SEL. Some schools emerged as exemplars in establishing relationship-based and equitable learning environments, offering explicit SEL instruction, and integrating SEL into academic instruction. In this report, they present examples from two innovative ObD high schools in which each of the three elements for supporting students' SEL were present.