This white paper describes instructional approaches that apply to successful teaching with the Smithsonian "Learning Lab." After defining its use of terms such as "deeper learning" and "authentic resources" the authors review the research basis of three broad approaches that support integrating digital resources into the classroom: project-based learning, guided exploration of concepts and principles, and guided development of academic skills. These approaches find practical application in the last section of the paper, which includes seven case studies. [This report was prepared for the Smithsonian Center for Learning and Digital Access by Interactive Educational Systems Design, Inc.]