The Comprehensive School Safety Initiative (CSSI) is a large-scale, integrated research effort designed to increase the safety of schools nationwide. It was initiated in 2014 at the request of Congress. The National Institute of Justice (NIJ) administers the CSSI as a research grant program. Through the CSSI, the NIJ funds research-focused projects that contribute to building a solid foundation of rigorously tested, objective, and independent knowledge and best practices about school safety. The CSSI is carried out through partnerships between researchers, educators, and other stakeholders (including professionals and agencies involved in law enforcement, behavioral and mental health, courts, and other parts of the justice system). The CSSI focuses on K-12 public schools (including public charter schools). It is concerned with all forms of violence that occur on school property during or outside of school hours, on the way to and from school or school-sponsored events, on school-sponsored modes of transport, or during school-sponsored events. This report responds to Senate Report 115-275 accompanying the Consolidated Appropriations Act, 2019 (P.L. 116-6) ("the Act"). It discusses the comprehensive school safety framework ("the framework") developed by the National Institute of Justice (NIJ). Findings arising out of research projects are funded through the CSSI. To provide additional information on materials used to develop the framework, the appendices included in the report offers a list of Federal resources on school safety and provides a list of products resulting from CSSI funding.