Of the 19 million students at U.S. colleges and universities in 2018, 28 percent were either first-generation immigrants or the children of immigrants. Together, these immigrant-origin students play an important role in postsecondary enrollment across the country, accounting for 58 percent of the growth of the student population between 2000 and 2018. Examining the characteristics of this population can help institutions of higher education and state education policymakers as they pursue the goal of equipping students with the skills and knowledge to meet the changing demands of the U.S. and local economies. Using data from the U.S. Census Bureau and other sources, this fact sheet offers a first-of-its-kind profile of immigrant-origin students in higher education, focusing specifically on "domestic students" and excluding international students (those who come for the purpose of education) to get the best picture of those who are established U.S. residents and either current or future U.S. workers. This analysis looks at how this population has grown over time, the states in which they make up large numbers and shares of all students, characteristics such as race/ethnicity and immigration status, and enrollment trends. [Support for this research came from the Presidents' Alliance for Higher Education and Immigration.]