Young people face particular disadvantage finding employment, compared to older workers. This includes a lack of labour market and job-search information and experience, as well as a mismatch between youth aspirations and labour market realities, with limited job led growth. The purpose of this paper is to provide guidance on how the United Nations Children's Fund (UNICEF) can support government and partners to support adolescents to make a smooth transition from school to decent work. Skills development is a necessary, but not sufficient, component of such programming. Specifically, this Technical Note provides advice on: (1) Barriers for young people in accessing and developing skills for work and making the transition to decent work; (2) Programming principles to guide the design of UNICEF programming in the school to work transition area; (3) Evidence-based strategies for smoothing the transition from school to work with a focus on improving the work outcomes for older adolescents and young people; (4) Tools and resources for developing programs and partnerships, including working with other UN agencies, to ensure continuity of services as the most vulnerable young people transition from childhood into adulthood; and (5) Case studies of UNICEF programs that have improved the skills and/or work outcomes of older adolescents. [This note was produced by the UNICEF Education Section. ING on the Power for Youth Programme provided funding which made development of this note possible.]