Universities UK is the collective voice of 136 universities in England, Scotland, Wales and Northern Ireland. The mission is to create the conditions for UK universities to be the best in the world; maximising their positive impact locally, nationally and globally. Universities UK leads collaboration among universities to ensure UK universities can maximise their positive impact. Universities UK priorities for 2018-2023 are presented in this strategic plan. The external environment for UK universities over the next five years will present a range of challenges as well as opportunities. Global political instability, including the UK's departure from the EU, national and regional devolution within the UK, a changing regulatory and funding environment, and increased pressures on universities to consistently and meaningfully provide evidence of value and impact, will require a thoughtful and strategic response from UK universities.