This first Early Implementers Initiative evaluation publication discusses one of the major shifts required by the Next Generation Science Standards (NGSS), namely the shift to integrated instruction. The integration of science and English language arts (ELA) is the focus of the first main section, and the integration of the science disciplines (i.e., earth and space, life, and physical) inherent in the middle school integrated model is the focus of the second. Also discussed in the third and final section, as well as throughout this publication, is another fundamental shift: the need to teach science in the first place. In order for any of the targeted shifts of the NGSS to take place, K-8 teachers must devote time to teaching science on a regular basis. Findings presented throughout the report are based on data from the eight public school districts supported by the S. D. Bechtel Jr., Foundation.