This brief describes examples of research and development (R&D) sponsored by the National Science Foundation (NSF) that are designed to advance knowledge and practice in science, technology, engineering, and mathematics (STEM) education. It highlights just a few of the many R&D projects that have the potential to equip educators in pursuing national priorities for STEM education. The national priorities cited in this report are among those identified in recent years by expert committees, with members drawn from the STEM professions, the military, business and industry, as well as from education policy, research, and practice. Under one NSF program, Discovery Research K-12 (DR K-12), grantees pursue research questions and develop resources, models, and tools for students and teachers in STEM. This report describes a sampling of DR K-12 projects that could, if successful, give life to the recommendations made by the experts. Staff of the Community Advancing Discovery Research in Education (CADRE) reviewed recent national reports to identify recommendations for STEM education that will depend on better resources, models, and tools for their enactment. CADRE identified nine priorities that recur across multiple reports, each having direct implications for practice in teaching and learning. For each priority, this brief presents several specific recommendations culled from the reports, followed by capsule descriptions of a few of the DR K-12 projects that are already working in these areas. These projects serve as examples, intended to illustrate the rich variety of work under way in the DR K-12 portfolio.