A quantitative, comparative, descriptive design was used to determine whether mixed online, on-ground educated graduates or on-ground educated graduates perform better as pharmaceutical sales representatives in the pharmaceutical sales industry. The number of students attending mixed online, on-ground institutions of higher learning has steadily increased upon the onset of online education in 1989. The specific problem addressed by this researcher was whether students from mixed online, on-ground colleges were as effective in the workplace as their counterparts at on-ground schools. The purpose for this quantitative, comparative, descriptive questionnaire design was to compare what is in the literature as it relates to the quality of education from mixed online, on-ground educated graduates versus on-ground educated graduates with actual sales results from pharmaceutical sales representatives. The participants included pharmaceutical sales representatives throughout the United States. Survey response data were analyzed using a one-way, between groups analysis of variance method. For research question one (RQ1), the difference between groups of school types were not statistically significant. For research question two (RQ2), the difference between groups based on school type was non-significant. For research question three (RQ3), the difference between groups was non-significant. For research question four (RQ4), the difference between the groups was non-significant. Based on the results of this study, employers should hire a greater number of employees who have participated in a mixed or all online education program to find out if the trend demonstrated in this study is replicated in practice. In addition, employers should encourage their sales employees to use technology to keep accurate sales records and to collaborate with other members of the sales organization to increase sales. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com.bibliotheek.ehb.be/en-US/products/dissertations/individuals.shtml.]