In May 2017, the Investing in Innovation Fund (i3) College Access and Success community embarked on a project to compile shared challenges and lessons learned as a resource for fellow i3 College Access and Success grantees, the larger community of i3 grantees, and the broader field of college access. Through this project, the authors discovered that many of the key challenges i3 College Access and Success grantees faced were not necessarily specific to their college access work, but related to the work of creating change and innovation and strong partnerships. As such, this paper may be of interest to all i3 grantees--regardless of whether their projects relate to college access and success--as well as to individuals working in the field of college access. Chapter 1 of this report introduces the i3 program and describes the i3 College Access and Success community and the development of this paper. Chapter 2 provides highlights of the key challenges i3 College Access and Success grantees reported, and maps the challenges to the grantee profiles in Chapter 4. Similarly, Chapter 3 shares key lessons learned, mapping the lessons learned to the grantee profiles in Chapter 4. Finally, Chapter 4 contains grantee profiles providing at-a-glance information about each participating grantee, as well as more in-depth discussion of their strategies, challenges, and lessons learned. [Contributing authors include: Karen M. Morris, Lara Dreier, Joel Vargas, Sarah Hooker, Elisabeth Barnett, Sarah Newman, Laureen Avery, Judy Saylor, Meg Grigal, Tom Duenwald, Suzanne Reeve, and Nicole Norfles.]