This is a structured abstract of a meta-analysis conducted by T. E. Scruggs, M. A. Mastropieri, S. Berkeley, and J. E. Graetz, published in "Remedial & Special Education" (2009). The authors of the original paper describe findings from a research synthesis on content area instruction for students with disabilities. Seventy studies were identified from a comprehensive literature search, examined, and coded for a number of variables, including weighted standardized mean-difference effect sizes. More than 2,400 secondary school students were participants in these investigations. Studies included interventions involving content areas, such as science, social studies, and English, and employed a number of different interventions, including study aids, classroom learning strategies, spatial and graphic organizers, mnemonic strategies, hands-on activities, classroom peers, and computer-assisted instruction. The overall effect size was 1.00, indicating an overall large effect across studies. Implications for future research and practice are described. [For "Do Special Education Interventions Improve Learning of Secondary Content? A Meta-Analysis," see EJ904253.]