Background: Over the last 20 years, Uganda has piloted and implemented various management information systems (MIS) for better surveillance of HIV/AIDS. With support from the United States Government, Uganda introduced the District Health Information Software 2 (DHIS2) in 2012. However, districts have yet to fully adapt to this system given a 70.2% reporting completeness achieved nationally between April-June 2013. Objectives: To examine factors associated with districts' incomplete reporting of HIV/AIDS data through DHIS2 and suggest policy recommendations. Methods: The study has one dependent variable: Districts' reporting completeness and four independent variables. 1.) Number of client visits; 2.) number of district health units; 3.) number of NGOs delivering HIV and AIDS services; and 4.) regional location of districts. These variables constituted overall study of reporting completeness obtained from "inpatient," "outpatient," and "maternal newborn health" by districts. Results: Districts that recorded the lowest number of client visits (under 2500) achieved the highest mean reporting completeness (81.6%), whereas a range of 2501-5000, or over 5001 client visits recorded 72.4% and 51.7% respectively. The higher the number of client visits the lower the reporting completeness (p < 0.0005). Districts that were receiving support from only one NGO recorded a mere 56.7% whereas those from two recorded 67.2%. Districts supported by over three NGOs had the highest (80.6%) mean reporting completeness score. The number of NGOs was statistically associated with reporting completeness p < 0.0005). The number of health units operated by a district was also significantly associated with reporting completeness (p < 0.0005). A consistent increase in the number of health units was associated with a consistent decrease in mean reporting completeness. The regional location of a district was not associated with reporting completeness (p = 0.674). Conclusion: The study recommended: districts with higher patient volume for HIV and AIDS services should be identified and targeted with additional NGO support; future NGOs support should be directed to districts that are operating over 40 health units. Incomplete reporting undermines evidence-based planning and service delivery for HIV prevention and antiretroviral therapy for all eligible population. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com.bibliotheek.ehb.be/en-US/products/dissertations/individuals.shtml.]