Learning is facilitated by conversational interactions both with human tutors and with computer agents that simulate human tutoring and ideal pedagogical strategies. In this article, we describe some intelligent tutoring systems (e.g., AutoTutor) in which agents interact with students in natural language while being sensitive to their cognitive and emotional states. These systems include one-on-one tutorial dialogues, conversational trialogues in which two agents (a tutor and a "peer") interact with a human student, and other conversational ensembles in which agents take on different roles. Tutorial conversations with agents have also been incorporated into educational games. These learning environments have been developed for different populations (elementary through high school students, college students, adults with reading difficulties) and different subjects spanning science, technology, engineering, mathematics, reading, writing, and reasoning. This article identifies some of the conversation patterns that are implemented in the dialogues and trialogues. [This article was published in "Current Directions in Psychological Science," v23 n5 p374-380 Oct 2014.]