Assessments of U.S. students typically reveal stronger performance in science than mathematics yet their science performance remains uninspiring at best. Whether the metric considered is an international benchmark from TIMSS or PISA or the nation's NAEP report card, the mediocre portrait of U.S. science achievement has remained virtually unchanged over the past 20 years. The Museum of Science and Industry, Chicago (MSI) is a readily accessible resource not only to the people of Chicago but also to a much larger multistate area. MSI has taken the initiative to establish an active and ongoing multifaceted working relationship with the Chicago Public Schools and other local schools, particularly those serving high-needs student populations. The issues of lackluster student achievement in science and science teachers' access to quality professional capacity-building experiences led MSI to form the Institute for Quality Science Teaching (IQST). This study's main focus was to evaluate the first of IQST's course goals, improving teachers' content knowledge, in one IQST course. The module selected for this evaluation project was the Get Re-Energized (GRE) module that focuses on energy topics, a part of the physical sciences and an area of particularly weak performance for U.S. students.