Discovering new ways to help students attain higher levels of scientific knowledge and to think critically is a national goal (Educate to Innovate campaign). Despite the best intentions, many students struggle to achieve a basic level of science knowledge (NAEP, 2011). The present study examined Talk Aloud Pair Problem Solving and frequency building with five students who were diagnosed with a disability and receive specialized reading instruction in a special education setting. Acquisition was obtained through scripted lessons and frequency building or practice strengthened the student's verbal repertoire making the problem solving process a durable behavior. Overall, students all demonstrated improvements in problem solving performance when compared to baseline. Students became more significantly accurate in performance and maintenance in learning was demonstrated. Generalization probes indicated improvement in student performance. Implications for practice and future research are discussed. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com.bibliotheek.ehb.be/en-US/products/dissertations/individuals.shtml.]