Student academic performance, persistence, and graduation among American Indian/Alaska Native students in higher education are very low compared to other racial groups. Studies have shown that American Indian students enter higher education with a lack of academic preparedness, financial challenges, lack of social skills development, and lack of role models needed to assist these students in completing their educational degrees. What remains unknown is whether or to what degree alcohol use by American Indian/Alaska Native students is a contributing factor in the low postsecondary success rates. The methodology involved a mixed methods approach among two tribal colleges. The findings concluded that there were no major differences between alcohol use and student academic performance and persistence and that there were no major differences between alcohol use and student graduation among two tribal colleges. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com.bibliotheek.ehb.be/en-US/products/dissertations/individuals.shtml.]