The federal "Promise Neighborhoods" program underscores the importance of all children and youth having "access to great schools and strong systems of family and community support that will prepare them to attain an excellent education and successfully transition to college and a career." From this perspective, this brief stresses the importance for grantees to use what has been learned about: (1) rethinking and coalescing existing programs and services in order to develop a unified and comprehensive system; and (2) establishing an effective school, home, and community collaborative to weave together different funding streams, reduce redundancy, and redeploy available resources. The brief also states that there is no reason for non-grantees to wait for findings from the demonstration projects. Any locale, despite sparse dollars, can use available resources to begin the process. As design aids, prototypes are offered for a unifying intervention framework and for a school, home, and community collaborative infrastructure. An appendix presents "About the Promising Neighborhoods Grants." (Contains 4 exhibits.)