The mission of the Nebraska Center for Research on Children, Youth, Families and Schools (CYFS) is to conduct research that improves our understanding of optimal ways that parents, teachers and other service providers in family, school and community contexts can promote the intellectual and socio-emotional development and behavioral adjustment of children and youth. Central to this is enhancing our understanding of how these systems can work together to support the future of our nation. The long-term goal of the Center is to become a nationally recognized center of excellence in research related to children and youth, and the multiple interrelated contexts in which they function (i.e., families, schools, and communities). This paper presents the annual report of the Center for 2005-2006. This report represents its most recent efforts at realizing "excellence." It provides a lens through which the Center looks forward with clarity, vigor, and a hope for impact that continues to catapult it to new and exciting levels. [For previous report, see ED538266.]