This report, which was commissioned as part of the Institute for Higher Education Policy's Walmart Minority Student Success Initiative, seeks to highlight how specific institutional policies and faculty-driven, classroom-based practices at Minority-Serving Institutions (MSIs) can change in an effort to better support the academic and social success of first-generation students. The report is structured in the following sections: (1) A brief summary of first-generation students as defined in literature and national data; (2) An overview of existing programs and resources that support first-generation students; and (3) A thematic breakdown of promising practices for improving first-generation student success, supported by examples from participating institutions. Through institutional examples, this report provides a road map for MSIs and other institutions hoping to enhance institutional capacity to better serve first-generation students. The success of this population is imperative to achieving overall gains in strengthening global competitiveness and national goals around postsecondary completion. (Contains 1 figure and 9 footnotes.)