According to the American Psychiatric Association, college can be an exciting time, though for some it can be overwhelming and stressful. Depression, anxiety, substance use, and eating disorders are common mental health issues on college campuses. The 2010 American College Health Association National College Health Assessment found that 28 percent of college students reported that at some point in the last 12 months they had felt so depressed it was hard to function. And 46 percent reported that, in the same period, they had experienced overwhelming anxiety. In addition, 8 percent of students also reported being diagnosed or treated for depression and almost 6 percent seriously considered suicide. This paper presents several research on depression and alcohol abuse among young adults in college. It also describes several alcohol and other drug services and mental health and counseling services at colleges and universities.