"Technology Enhanced Elementary and Middle School Science" ("TEEMSS") is a physical science curriculum for grades 3-8 that utilizes computers, sensors, and interactive models to support investigations of real-world phenomena. Through 15 inquiry-based instructional units, students interact with computers, gather and analyze data, and formulate ideas for further exploration. This information is managed by software in a handheld computer and transmitted to other students and to the teacher. All classroom units use handheld computers to avoid the expense of networked desktop computers. The program includes a web-based teacher-reporting tool that allows teachers to review student portfolios and gather student responses for assessment and class discussion. Three studies reviewed by the What Works Clearinghouse (WWC) investigated the effects of "TEEMSS" on elementary school students. One study (Zucker, Tinker, Staudt, Mansfield, & Metcalf, 2008) is a quasi-experimental design that meets WWC evidence standards with reservations. This study is summarized in this report. The remaining two studies do not meet either WWC eligibility screens or evidence standards. Appended are: (1) Research details for Zucker et al. (2008); (2) Outcome measures for each domain; and (3) Findings included in the rating for the general science achievement domain. A glossary of terms is included. (Contains 4 tables, 8 endnotes and 1 additional source.)