The purpose of this state report card is to provide the general public and policymakers with information they can use to assess and improve postsecondary education in each state. "Measuring Up 2006" is the fourth in a series of biennial report cards. The report card grades states in six overall performance categories: (1) Preparation: How adequately does the state prepare students for education and training beyond high school?; (2) Participation: Do state residents have sufficient opportunities to enroll in education and training beyond high school?; (3) Affordability: How affordable is higher education for students and their families?; (4) Completion: Do students make progress toward and complete their certificates or degrees in a timely manner?; (5) Benefits: What benefits does the state receive from having a highly educated population?; and (6) Learning: What is known about student learning as a result of education and training beyond high school? Findings for Missouri include: (1) Missouri has made gains in preparing students to succeed in college. This year Missouri receives a C in preparation; (2) Missouri continues its consistently good performance in the number of students enrolling in higher education. Missouri continues that performance this year, earning a B in participation; (3) Missouri has made no notable progress in providing affordable higher education. Missouri receives an F in affordability this year; (4) Missouri has shown substantial improvement in the proportion of students earning their certificates or degrees in a timely manner. This year Missouri receives a B+ in completion; (5) Missouri has made substantial gains in the benefits the state receives from having a highly educated population. This year Missouri earns an A in benefits; and (6) Missouri is among nine states that receive a "Plus" in Learning because data were sufficient to compare at least two of the three Learning categories in the state results described in this paper. This report also includes international comparisons, additional information, questions and answers, and state grades. (Contains 1 figure.) [For "Measuring Up, 2006. The National Report Card on Higher Education," see ED493360.]