This study utilized both quantitative and qualitative methods in investigating how a novel science curriculum, geared towards the 21st century student, affected skills and attitudes towards science for tenth grade students. The quantitative portion of the study was a quasi-experimental design since random groups were not possible. This portion of the study used a pretest/posttest design to measure any improvement in science skills, and a Likert scale survey to measure any improvements in students' attitudes. Statistical tests revealed no significant differences between students who received the novel curriculum versus those students who received a traditional curriculum. Both groups showed significant improvements in all skill areas. Qualitatively, the researcher used informal teacher interviews and student surveys to identify the most relevant and effective curriculum components for the 21st century student. The findings suggest that the task of creating a meaningful and relevant curriculum based on the necessary skills of this century is not an easy task. There is much more work to be done in this area, but according to the qualitative findings integrated design and student technology are promising. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com.bibliotheek.ehb.be/en-US/products/dissertations/individuals.shtml.]